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D-159404

CAT: 0931-T201976-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201976-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1158221-32-9
Bioactivity
D-159404, as an allosteric inhibitor, demonstrates superior inhibitory effects on the full-length PDE 4D3 compared to its truncated form and exhibits higher cellular activity. This sets it apart from competitive inhibitors like roflumilast and cilomilast. These findings indicate that D-159404 and related compounds may offer valuable insights into PDE 4 pharmacology and serve as strong candidates for further study on cAMP signaling's impact on disease treatment.
Smiles
O=C(N)NC1=CC=C(C=C1)CC=2C=CC(OC)=C(C3=CC=CC(Cl)=C3)C2F
Molecular Formula
C21H18ClFN2O2
Molecular Weight
384.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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