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22-Hydroxy mifepristone

CAT: 0931-T201780-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201780-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
105012-15-5
Target
Endogenous Metabolite, Glucocorticoid Receptor
Related Pathways
Endocrinology/Hormones, Metabolism
Bioactivity
22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.
Smiles
C[C@@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(N(C)C)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(C#CCO)O)[H]
Molecular Formula
C29H35NO3
Molecular Weight
445.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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