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PROTAC IRAK4 ligand-4

CAT: 0931-T201660-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201660-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2434841-55-9
Target
IRAK, Ligands for Target Protein for PROTAC
Related Pathways
Immunology/Inflammation, NF-κB, PROTAC
Bioactivity
PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.
Smiles
N(C(=O)C=1N=C(OC1)C=2C=C(NCC3CC3)N=CC2)C4=CN(N=C4C(F)F)[C@H]5CC[C@H](C=O)CC5
Molecular Formula
C24H26F2N6O3
Molecular Weight
484.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

2-[2-(cyclopropylmethylamino)pyridin-4-yl]-N-[3-(difluoromethyl)-1-(4-formylcyclohexyl)pyrazol-4-yl]-1,3-oxazole-4-carboxamide
CAS Number2434841-55-9
PubChem CID146598804
IUPAC Name2-[2-(cyclopropylmethylamino)-4-pyridinyl]-N-[3-(difluoromethyl)-1-(4-formylcyclohexyl)pyrazol-4-yl]-1,3-oxazole-4-carboxamide
Molecular FormulaC24H26F2N6O3
Molecular Weight484.5
XLogP2.8
Topological Polar Surface Area115
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Heavy Atom Count35
Formal Charge0
Complexity736
SMILES
C1CC1CNC2=NC=CC(=C2)C3=NC(=CO3)C(=O)NC4=CN(N=C4C(F)F)C5CCC(CC5)C=O
InChI
InChI=1S/C24H26F2N6O3/c25-22(26)21-18(11-32(31-21)17-5-3-15(12-33)4-6-17)29-23(34)19-13-35-24(30-19)16-7-8-27-20(9-16)28-10-14-1-2-14/h7-9,11-15,17,22H,1-6,10H2,(H,27,28)(H,29,34)
InChIKey
CKFRBTHREJJPGO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-[2-(cyclopropylmethylamino)pyridin-4-yl]-N-[3-(difluoromethyl)-1-(4-formylcyclohexyl)pyrazol-4-yl]-1,3-oxazole-4-carboxamide
CAS: 2434841-55-9
CID: 146598804
Formula: C24H26F2N6O3
MW: 484.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight484.5
XLogP32.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Exact Mass484.20344504
Monoisotopic Mass484.20344504
Topological Polar Surface Area115 Ų
Heavy Atom Count35
Formal Charge0
Complexity736
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T81378-01PROTAC IRAK4 ligand-3
T13843-01PROTAC IRAK4 ligand-1
T201571-01PROTAC IRAK4 ligand-5
T39901-01PROTAC IRAK4 degrader-4
T211666-01PROTAC BRD4 ligand-4
T211884-01PROTAC IRAK4 degrader-13
T88159-01PROTAC IRAK4 degrader-10
T74062-01PROTAC IRAK4 degrader-2
T39903-01PROTAC IRAK4 degrader-6
T201267-01PROTAC IRAK4 degrader-12

Alternative Products

CatalogName
GTR19240454-01PROTAC IRAK4 ligand-4
GTR19218640-01PROTAC IRAK4 ligand-3
HY-168311PROTAC IRAK4 ligand-5
HY-129967-01PROTAC IRAK4 ligand-1
GTR19222241-01PROTAC IRAK4 degrader-4
HY-175242PROTAC BRD4 ligand-4
MBS5800292PROTAC IRAK4 degrader-3
MBS5820758PROTAC IRAK4 degrader-8
BUP21150-01PROTAC IRAK4 degrader-1
HY-139317PROTAC IRAK4 degrader-6

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