SJ46411-Br

• Target:

  Ligand for E3 Ligase

• Related Pathways:

  PROTAC

• Bioactivity:

  SJ46411-Br is an orally effective CK1? molecular glue (Molecular Glue) degrader. It binds with CRL2^KLHDC2 to facilitate the formation of a cooperative homoselective ternary complex. Furthermore, SJ46411-Br is coupled with the BET ligand JQ1 through a PROTAC linker, enabling the synthesis of corresponding PROTACs.

• Molecular Formula:

  C17H13BrN2O3S

• Molecular Weight:

  405.27

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C