SJ46411-Br

• Target :

  Ligand for E3 Ligase

• Related Pathways :

  PROTAC

• Bioactivity :

  SJ46411-Br is an orally effective CK1? molecular glue (Molecular Glue) degrader. It binds with CRL2^KLHDC2 to facilitate the formation of a cooperative homoselective ternary complex. Furthermore, SJ46411-Br is coupled with the BET ligand JQ1 through a PROTAC linker, enabling the synthesis of corresponding PROTACs.

• Molecular Formula :

  C17H13BrN2O3S

• Molecular Weight :

  405.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C