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Br-PBTC

CAT: 0931-T39286Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T39286Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1839519-57-1
Target
Others, AChR
Related Pathways
Others, Neuroscience
Bioactivity
Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs) . It specifically targets α2β2, α2β4, α4β2, α4β4, (α4β2) 2α4, and (α4β2) 2β2 subtypes of nAChRs, with EC50 values ranging from 0.1 to 0.6 μM. Br-PBTC exerts its activity by binding to the c-tail region of an α subunit.
Smiles
Brc1cccc2cc(sc12)C(=O)N[C@@H]1CCCNC1
Molecular Formula
C14H15BrN2OS
Molecular Weight
339.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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