Br-PBTC

• Target:

  Others|||AChR

• Related Pathways:

  Others|||Neuroscience

• Bioactivity:

  Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs) . It specifically targets ?2?2, ?2?4, ?4?2, ?4?4, (?4?2) 2?4, and (?4?2) 2?2 subtypes of nAChRs, with EC50 values ranging from 0.1 to 0.6 ?M. Br-PBTC exerts its activity by binding to the c-tail region of an ? subunit.

• Smiles:

  Brc1cccc2cc(sc12)C(=O)N[C@@H]1CCCNC1

• Molecular Formula:

  C14H15BrN2OS

• Molecular Weight:

  339.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1839519-57-1