MLS-0053105

CAT: 0931-MF-0110828-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0110828-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
370572-36-4
Target
Bcl-2 Family|||FXR
Related Pathways
Metabolism|||Apoptosis
Bioactivity
MLS-0053105, a chloromaleimide, functions as a selective inhibitor of BFL-1, exhibiting an IC50 of 0.4 µM against Bfl-1/F-Bid. Its inhibitory potency is over tenfold lower for Bcl-W, Bcl-2, and Bcl-XL, and it shows no activity against Bcl-B and Mcl-1.
Smiles
O=C1C(Cl)=C(C(=O)N1C2=CC=C(Cl)C(Cl)=C2)N3CCN(C)CC3
Molecular Formula
C15H14Cl3N3O2
Molecular Weight
374.65
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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