MLS-0053105

• CAS Number :

  370572-36-4

• Target :

  Bcl-2 Family|||FXR

• Related Pathways :

  Metabolism|||Apoptosis

• Bioactivity :

  MLS-0053105, a chloromaleimide, functions as a selective inhibitor of BFL-1, exhibiting an IC50 of 0.4 µM against Bfl-1/F-Bid. Its inhibitory potency is over tenfold lower for Bcl-W, Bcl-2, and Bcl-XL, and it shows no activity against Bcl-B and Mcl-1.

• Smiles :

  O=C1C(Cl)=C(C(=O)N1C2=CC=C(Cl)C(Cl)=C2)N3CCN(C)CC3

• Molecular Formula :

  C15H14Cl3N3O2

• Molecular Weight :

  374.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C