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I194496

CAT: 0931-T201096-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T201096-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
445238-07-3
Target
Annexin A, Akt, VEGFR, FAK, ERK, PI3K, Ras, Raf, STAT, Others
Related Pathways
Cytoskeletal Signaling, GPCR/G Protein, MAPK, Others, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Angiogenesis
Bioactivity
I194496 is an effective inhibitor of cystathionine γ-lyase (CSE) with an IC50 value of 0.79 mM. It inhibits the growth of human TNBC cells by dual targeting the PI3K/Akt and Ras/Raf/ERK pathways. Additionally, I194496 suppresses the metastasis of human TNBC cells by downregulating the Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways.
Smiles
O=C(NC1=CC=C(C=C1)S(=O)(=O)NC=2C=CC=CC2OC)C=3C=NN4C3N=C(C=C4C(F)F)C=5C=CC(OC)=CC5
Molecular Formula
C28H23F2N5O5S
Molecular Weight
579.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19239692-01I194496
A24248-100I194496 100mg
A24248-50I194496 50mg
A24248-10I194496 10mg
A24248-5I194496 5mg

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