UNC0638 hydrate

• Target:

  Histone Methyltransferase|||Influenza Virus|||Autophagy

• Related Pathways:

  Microbiology/Virology|||Chromatin/Epigenetic|||Autophagy

• Bioactivity:

  UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.

• Smiles:

  O.N=1C=2C=C(OCCCN3CCCC3)C(OC)=CC2C(=NC1C4CCCCC4)NC5CCN(CC5)C(C)C

• Molecular Formula:

  C30H49N5O3

• Molecular Weight:

  527.74

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1255517-77-1