PS-166276

• Target:

  P38 MAPK

• Related Pathways:

  MAPK

• Bioactivity:

  PS-166276 is a potent p38 inhibitor with low cytotoxicity. It exhibits an IC50 value of 28 nM against p38 kinase and an IC50 of 170 nM in the THP-1 TNF? assay.

• Smiles:

  N(C=1N=C(N[C@@H]2CCNC2)N=C(N(CC(C)C)C)N1)C3=CC(C(N)=O)=CC=C3C

• Molecular Formula:

  C20H30N8O

• Molecular Weight:

  398.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  348089-57-6