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Rosiglitazone sodium

CAT: 0931-T200945-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T200945-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
316371-83-2
Target
Autophagy, PPAR, TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel, Autophagy, Metabolism, DNA Damage/DNA Repair
Bioactivity
Rosiglitazone sodium is an effective and selective PPARγ activator, with EC50 values of 30 nM for PPARγ1, 100 nM for PPARγ2, and 60 nM for PPARγ. It also has an approximate Kd of 40 nM for PPARγ. Additionally, Rosiglitazone sodium acts as a regulator of TRP channels, inhibiting the activities of TRPM2 and TRPM3, while activating TRPC5.
Smiles
O=C1SC(CC2=CC=C(C=C2)OCCN(C)C3=NC=CC=C3)C([N-]1)=O.[Na+]
Molecular Formula
C18H18N3NaO3S
Molecular Weight
379.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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