Rosiglitazone potassium

CAT: 0931-MF-0006601-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0006601-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
316371-84-3
Target
Ferroptosis|||Apoptosis|||Autophagy|||Others|||PPAR|||TRP/TRPV Channel
Related Pathways
Metabolism|||Autophagy|||Membrane transporter/Ion channel|||Apoptosis|||DNA Damage/DNA Repair|||Others
Bioactivity
Rosiglitazone (BRL 49653) potassium, a potent and selective PPAR? agonist (EC 50: 60 nM, Kd: 40 nM) administered orally, also acts as an activator of TRPC5 (EC 50: 30 ?M) and an inhibitor of TRPM3. Widely used in research, it has shown promise in investigating obesity, diabetes, senescence, and ovarian cancer [1] [2] [4] [7].
Smiles
[K+].CN(CCOc1ccc(CC2SC(=O)[N-]C2=O)cc1)c1ccccn1
Molecular Formula
C18H18KN3O3S
Molecular Weight
395.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C