WEE1-IN-11

• Target:

  Wee1

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  WEE1-IN-11 (Compound 13) serves as a potent CDK2 inhibitor with an IC50 of 2.0 nM. It exhibits inhibitory effects on several cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr, with respective IC50 values of 93.9, 34.5, 86.7, 23.1, and 85 nM.

• Smiles:

  N(C=1N=C(C(=CN1)C2=CN=CS2)C=3SC(=NC3)N4CC[C@H](F)C4)C5=CC(OC)=C(C=C5)N6CCN(C)CC6

• Molecular Formula:

  C26H29FN8OS2

• Molecular Weight:

  552.69

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2975172-98-4