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MRS4833

CAT: 0931-T200837-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T200837-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2801627-78-9
Target
P2Y Receptor
Related Pathways
GPCR/G Protein|||Neuroscience
Bioactivity
MRS4833 (compound 15) is an orally active, potent, competitive antagonist of P2Y14R, exhibiting IC50 values of 5.92 nM for hP2Y14R and 4.8 nM for mP2Y14R. It reduces airway eosinophilia in protease-mediated asthma models and reverses chronic neuropathic pain in mouse CCI models.
Smiles
O[C@]1([C@@]2(C[C@]1(CNC2)[H])[H])C3=CC=C(C=C3)C=4C5=C(C=C(C=C5)C6=CC=C(C(F)(F)F)C=C6)C=C(C(O)=O)C4
Molecular Formula
C30H24F3NO3
Molecular Weight
503.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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