Cetzole

CAT: 0931-MF-0142639-01Size: 25 mgDry Ice: NoHazardous: No

CAT#:0931-MF-0142639-01Size:25 mg

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AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3043764-86-6

Target

Ferroptosis

Related Pathways

Apoptosis

Bioactivity

Cetzole (Compound 1) acts as an inducer of ferroptosis (iron-dependent cell death) through the accumulation of ROS, leading to cell death. The compound exhibits varying half-maximal cytotoxic concentrations (CC50) against several cell lines: 2.56 ?M in NCI-H522, 10.31 ?M in NCI-H522 GFP-SCL7A11 #8, 2.71 ?M in NCI-H522 RV-GFP, 3.07 ?M in HT-1080, 14.9 ?M in NARF2, and 6.28 ?M in MDA-MB-231. This highlights Cetzole's potential for research in cancer therapeutics.

Smiles

C#CC1=NC(=CS1)C2=C(C)C(O)CC2

Molecular Formula

C11H11NOS

Molecular Weight

205.28

Shipping Conditions

Cool pack

Storage Temperature

-20°C