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D228

CAT: 0931-T200551-05Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T200551-05Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2676188-98-8
Target
IL Receptor, p38 MAPK, MyD88
Related Pathways
Immunology/Inflammation, MAPK
Purity
0.9991
Bioactivity
D228, a natural product from Chimonanthus salicifolius, is an orally available anti-inflammatory agent with favorable inhibitory activity on B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10 to reduce inflammation, and can be used for the treatment of inflammatory bowel disease (IBD) .
Smiles
O([C@H]1[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)C=2C(=O)C(=C(C)C)OC2C
Molecular Formula
C22H28O12
Molecular Weight
484.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

[(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2-methyl-4-oxo-5-propan-2-ylidenefuran-3-yl)oxyoxan-2-yl]methyl acetate
CAS Number2676188-98-8
PubChem CID156516634
IUPAC Name[(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2-methyl-4-oxo-5-propan-2-ylidenefuran-3-yl)oxyoxan-2-yl]methyl acetate
Molecular FormulaC22H28O12
Molecular Weight484.4
XLogP1.7
Topological Polar Surface Area150
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count12
Rotatable Bond Count11
Heavy Atom Count34
Formal Charge0
Complexity926
SMILES
CC1=C(C(=O)C(=C(C)C)O1)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C
InChI
InChI=1S/C22H28O12/c1-9(2)17-16(27)18(10(3)29-17)34-22-21(32-14(7)26)20(31-13(6)25)19(30-12(5)24)15(33-22)8-28-11(4)23/h15,19-22H,8H2,1-7H3/t15-,19-,20+,21-,22+/m1/s1
InChIKey
GLNKLSQINQQSFI-JLMLEOCNSA-N
Chemical Structure
2D Structure
2D structure of [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-(2-methyl-4-oxo-5-propan-2-ylidenefuran-3-yl)oxyoxan-2-yl]methyl acetate
CAS: 2676188-98-8
CID: 156516634
Formula: C22H28O12
MW: 484.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight484.4
XLogP31.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count12
Rotatable Bond Count11
Exact Mass484.15807632
Monoisotopic Mass484.15807632
Topological Polar Surface Area150 Ų
Heavy Atom Count34
Formal Charge0
Complexity926
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-164670-01D228
GTR18042079-01Six3/6 (D228) polyclonal antibody

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