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ZLY06

CAT: 0931-T200490-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200490-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2834727-04-5
Target
PPAR, Akt
Related Pathways
Cytoskeletal Signaling, DNA Damage/DNA Repair, Metabolism, PI3K/Akt/mTOR signaling
Bioactivity
ZLY06 is a dual agonist of peroxisome proliferator-activated receptors (PPAR) δ and γ with oral activity (PPAR δ: EC50=341 nM; PPARγ: EC50=237 nM) . It mediates the upregulation of CD36 and induces hepatic lipid accumulation by inhibiting the phosphorylation of AKT1. Moreover, ZLY06 significantly improves glucose and lipid metabolism without increasing body weight, primarily by enhancing the β-oxidation of fatty acids and reducing hepatic lipid synthesis, thereby alleviating fatty liver disease.
Smiles
O=C\1C=2C(O/C1=C\C3=CC(C)=C(OC(C(O)=O)(C)C)C(C)=C3)=CC(OCC4CC4)=CC2
Molecular Formula
C25H26O6
Molecular Weight
422.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-168049-01ZLY06

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