Products for Research Use Only

BHA536

CAT: 0931-T200350-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200350-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
919992-85-1
Target
NF-κB, Apoptosis, PKC
Related Pathways
NF-κB, Apoptosis, Chromatin/Epigenetic, Cytoskeletal Signaling
Bioactivity
BHA536 is an orally effective inhibitor of PKCα/β and the NF-kB signaling pathway. This compound inhibits the proliferation of ABC DLBCL cells harboring CD79 mutations by causing cell cycle arrest in the G1 phase and induces apoptosis in TMD8 cells. Additionally, BHA536 exhibits antitumor activity in mice.
Smiles
O=C1NC(=O)C(C2=C(Cl)C=CC3=CC=C(C=C32)CN(C)C)=C1C4=CNC=5C(OCCOCCOC)=CC=CC45
Molecular Formula
C30H30ClN3O5
Molecular Weight
548.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-164462BHA536