Top1/2-IN-1

CAT: 0931-T200315-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T200315-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Topoisomerase

Related Pathways

DNA Damage/DNA Repair

Bioactivity

Compound 23, known as Top1/2-IN-1, is a dual inhibitor of Top1/2 that can be administered orally and exhibits antiproliferative effects. It induces apoptosis and cell cycle arrest in cancer cells by damaging DNA and elevating reactive oxygen species levels. Additionally, Top1/2-IN-1 demonstrates antitumor activity in vivo within xenograft models.

Molecular Formula

C21H21N3O2

Molecular Weight

347.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-161957	Top1/2-IN-1
HY-159935	Top1-IN-2
GTR19204607-01	Top1 inhibitor 1
529210-01	TOP1
T5008-76B	Thimet Oligopeptidase 1 (TOP1)
A13304-1	Top1 inhibitor 1 1mg
A13304-100	Top1 inhibitor 1 100mg
A13304-25	Top1 inhibitor 1 25mg
A13304-5	Top1 inhibitor 1 5mg
A13304-50	Top1 inhibitor 1 50mg

Top1/2-IN-1

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