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MMs02943764

CAT: 0931-T200273-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200273-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
708287-29-0
Target
MDM-2/p53
Related Pathways
Apoptosis
Bioactivity
MMs02943764, a derivative of 1,2,4-triazole, exhibits anticancer activity. This compound demonstrates significant antiproliferative effects across various cancer cell lines. Its structural analog, PAC, shows notable cytotoxicity towards the leukemia cell line K562 (IC50=35.264 μM), functioning by inhibiting Mdm2 and Pirh2 to reduce degradation of p53 and consequently inducing cell cycle arrest in K562 cells.
Smiles
O=C(NC=1C(F)=CC(F)=CC1Br)CSC2=NN=C(N2CC=C)COC3=CC(=CC=C3C(C)C)C
Molecular Formula
C24H25BrF2N4O2S
Molecular Weight
551.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-158968-01MMs02943764

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