CIB-1476

CAT: 0931-T200261-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T200261-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
NOD-like Receptor (NLR) |||NF-?B|||Pyroptosis|||Caspase
Related Pathways
Immunology/Inflammation|||NF-?B|||Apoptosis|||Proteases/Proteasome
Bioactivity
CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1? production, NF-?B activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.
Molecular Formula
C28H28N2O6S
Molecular Weight
520.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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