INI-4001

• Target :

  TLR

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  INI-4001, a TLR7/8 agonist, exhibits EC50 values of 1.89 ?M and 4.86 ?M for TLR7 and TLR8, respectively. This compound induces signal transduction and SEAP production through TLR7 and TLR8. Furthermore, INI-4001 stimulates the production of high-affinity, fentanyl-specific antibodies, effectively preventing fentanyl from crossing the human blood-brain barrier. It serves as an effective adjuvant in anti-fentanyl vaccines for individuals with opioid use disorder (OUD) .

• Smiles :

  C(N1C=2C(NC1=O)=C(N)N=C(O[C@H](CCC)C)N2)C3CCN(CCOP(OCCOCCOCCOC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(=O)O)CC3

• Molecular Formula :

  C59H109N6O13P

• Molecular Weight :

  1141.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2549050-07-7