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INI-4001

CAT: 0931-T200260-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T200260-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2549050-07-7
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
INI-4001, a TLR7/8 agonist, exhibits EC50 values of 1.89 ?M and 4.86 ?M for TLR7 and TLR8, respectively. This compound induces signal transduction and SEAP production through TLR7 and TLR8. Furthermore, INI-4001 stimulates the production of high-affinity, fentanyl-specific antibodies, effectively preventing fentanyl from crossing the human blood-brain barrier. It serves as an effective adjuvant in anti-fentanyl vaccines for individuals with opioid use disorder (OUD) .
Smiles
C(N1C=2C(NC1=O)=C(N)N=C(O[C@H](CCC)C)N2)C3CCN(CCOP(OCCOCCOCCOC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(=O)O)CC3
Molecular Formula
C59H109N6O13P
Molecular Weight
1141.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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