Products for Research Use Only
RegisterLogin

NCAO

CAT: 0931-T200215-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T200215-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
20584-81-0
Target
Apoptosis, Others
Related Pathways
Others, Apoptosis
Bioactivity
N-ω-chloroacetyl-L-ornithine (NCAO) serves as a powerful reversible competitive inhibitor of ornithine decarboxylase (ODC), displaying cytotoxic and antiproliferative properties against various tumor cell lines, with EC50 values spanning from 1 to 50.6 μM. In vitro studies reveal that NCAO promotes Apoptosis and restricts tumor cell migration. Additionally, it demonstrates significant antitumor efficacy in a mouse model, targeting both solid and ascitic tumors using the myeloma (Ag8) cell line. NCAO holds promise in the development of antitumor agents.
Smiles
C([C@@H](C(O)=O)N)CCNC(CCl)=O
Molecular Formula
C7H13ClN2O3
Molecular Weight
208.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
TMAH-00805-01Anti-NCAM Antibody (6L815)
TMAB-09267Anti-NCAM Antibody (2S376)
TMAB-09268-01Anti-NCAM Antibody (1T37)
TMAB-09269-01Anti-NCAM/CD56 Antibody (7V279)
T205792-01MC-ADAA-S-NCA-DM1

Alternative Products

CatalogName
GTR19239153-01NCAO

Popular Products