FO-4-15

CAT: 0931-T200203-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T200203-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1030759-58-0

Target

GluR, CaMK, Microtubule Associated

Related Pathways

Neuroscience, Cytoskeletal Signaling

Bioactivity

FO-4-15 is an activator of mGluR1/CaMKIIα. It exhibits protective effects against H2O2 in human neuroblastoma (SH-SY5Y) cells. In mice with Alzheimer's disease, FO-4-15 enhances cognitive function by activating the mGluR1/CaMKIIα pathway, reducing Aβ accumulation, Tau hyperphosphorylation, and synaptic damage.

Smiles

O=S(=O)(C1=CC=C(C=C1)C)N2CCN(CC3=NC(=NO3)C=4OC=CC4)CC2

Molecular Formula

C18H20N4O4S

Molecular Weight

388.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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