XMU-MP-9

• CAS Number :

  2251130-41-1

• Target :

  Ras

• Related Pathways :

  MAPK|||GPCR/G Protein

• Bioactivity :

  XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.

• Smiles :

  O=C(NCC=1C(F)=CC=CC1Cl)C2=CSC(=C2)C3=NNC=4C=CC=CC34

• Molecular Formula :

  C19H13ClFN3OS

• Molecular Weight :

  385.84

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C