XMU-MP-9

• Target:

  Ras

• Related Pathways:

  MAPK|||GPCR/G Protein

• Bioactivity:

  XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.

• Smiles:

  O=C (NCC=1C (F) =CC=CC1Cl) C2=CSC (=C2) C3=NNC=4C=CC=CC34

• Molecular Formula:

  C19H13ClFN3OS

• Molecular Weight:

  385.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2251130-41-1