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PF-3837

CAT: 0931-T200061-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T200061-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2772910-13-9
Target
Kinesin|||Apoptosis
Related Pathways
Cytoskeletal Signaling|||Apoptosis
Bioactivity
PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis) . PF-3837 is utilized in the study of breast cancer.
Smiles
N#CC1=CNC2=NC(=NC(NC(C)(C)CO)=C12)NC3=CC=C(N=C3C)N4CCOCC4
Molecular Formula
C21H26N8O2
Molecular Weight
422.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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