PF-3837

• Target :

  Kinesin|||Apoptosis

• Related Pathways :

  Cytoskeletal Signaling|||Apoptosis

• Bioactivity :

  PF-3837 is an inhibitor of the Mps1 kinase, with a Ki value of 0.33 nM and an IC50 value of 5.5 nM. It disrupts cell cycle checkpoints by inhibiting the catalytic activity of Mps1, thereby reducing genomic stability and leading to cancer cell apoptosis (Apoptosis) . PF-3837 is utilized in the study of breast cancer.

• Smiles :

  N#CC1=CNC2=NC(=NC(NC(C)(C)CO)=C12)NC3=CC=C(N=C3C)N4CCOCC4

• Molecular Formula :

  C21H26N8O2

• Molecular Weight :

  422.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2772910-13-9