(2R,3S) -Azelaprag

• Target:

  Apelin receptor

• Related Pathways:

  GPCR/G Protein

• Purity:

  >99.99%

• Bioactivity:

  (2R,3S) -N- (4- (2,6-dimethoxyphenyl) -5- (5-methylpyridin-3-yl) -4H-1,2,4-triazol-3-yl) -3- (5-methylpyrimidin-2-yl) butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM. (2R,3S) -N- (4- (2,6-dimethoxyphenyl) -5- (5-methylpyridin-3-yl) -4H-1,2,4-triazol-3-yl) -3- (5- methylpyrimidin-2-yl) butane-2-sulfonamide is used in the treatment of heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke and myocardial infarction.

• Smiles:

  N(S([C@@H]([C@@H](C)C=1N=CC(C)=CN1)C)(=O)=O)C=2N(C(=NN2)C=3C=C(C)C=NC3)C4=C(OC)C=CC=C4OC

• Molecular Formula:

  C25H29N7O4S

• Molecular Weight:

  523.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2049979-31-7