EG01377

• Target:

  Others|||Complement System

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 ?M for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.

• Smiles:

  S(NC1=C(C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)SC=C1)(=O)(=O)C2=C3C(=CC(=C2)C4=CC=C(CN)C=C4)CCO3

• Molecular Formula:

  C26H30N6O6S2

• Molecular Weight:

  586.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2227996-00-9