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Recombinant Human CD68 Protein

CAT: 1510-BRP1154Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1510-BRP1154Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia) .Human CD68 is a Type I transmembrane glycoprotein, heavily glycosylated in its extracellular domain, with a molecular weight of 110 kD. Its primary sequence consists of 354 amino acids with predicted molecular weight of 37.4 kD if it were not glycosylated.
Description
Recombinant human CD68 Protein with the Fc region of human IgG1 at the C-terminus
Synonyms
GP110, LAMP4, SCARD1, Cluster of Differentiation 68
Source
HEK293 Cells
Applications
SDS-PAGE
Endotoxin
<1.0 EU per μg of the protein as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
References & Citations
Holness CL, Simmons DL (March 1993) . "Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins". Blood. 81 (6) : 1607–13. "CD68 - Macrosialin precursor - Homo sapiens (Human) - CD68 gene & protein".
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Lyophilized

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