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Recombinant Human CD11C Protein

CAT: 1510-BRP1153Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1510-BRP1153Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c.CD11c is an integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Description
Recombinant human CD11C protein with his tag.
Synonyms
CD11C, SLEB6, ITGAX, integrin subunit alpha X
Source
HEK293 Cells
Applications
SDS-PAGE
Endotoxin
<1.0 EU per μg of the protein as determined by the LAL method
Purity
>90% by SDS-PAGE
Buffer
Each vial Lyophilized from 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.
References & Citations
"Entrez Gene: ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) ". Dyer KD, Garcia-Crespo KE, Killoran KE, Rosenberg HF (2011) . "Antigen profiles for the quantitative assessment of eosinophils in mouse tissues by flow cytometry". Journal of Immunological Methods. 369 (1–2) : 91–7.
Storage Conditions
Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
Formulation
Lyophilized

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