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Recombinant human SNAP25 protein

CAT: 0112-SNP0601-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-SNP0601-020Size:20 µg
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Description
The synaptosomal-associated protein (SNAP-25) is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters. Recombinant human SNAP25, fused to His tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Synaptosomal-associated protein 25 isoform SNAP25B, SNAP25, SNAP, SNAP25, Synaptosomal-associated protein, His- tag, SNAP-25, Synaptosomal-associated 25 kDa protein, Super protein, SuP, Synaptosomal-associated protein 25, Synaptosomal-associated protein 25 isoform SNAP25B bA416N4.2, Bdr, dJ1068F16.2, FLJ23079, HGNC:11132, MGC105414, MGC139754, Resistance to inhibitors of cholinesterase 4 homolog, RIC 4, RIC4, SEC9, SNAP 25, SNAP-25B, SNP 25, sp, Synaptosomal associated 25 kDa protein, Synaptosomal associated protein, Synaptosomal Associated Protein 25, Synaptosomal associated protein 25kDa.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
25.4 kDa (226aa) confirmed by MALDI-TOF
Additionnal Information
SNAP25, Synaptosomal-associated protein 25 isoform SNAP25B, SNAP25, SNAP, SNAP25, Synaptosomal-associated protein, His- tag, SNAP-25, Synaptosomal-associated 25 kDa protein, Super protein, SuP, Synaptosomal-associated protein 25, Synaptosomal-associated protein 25 isoform SNAP25B bA416N4.2, Bdr, dJ1068F16.2, FLJ23079, HGNC:11132, MGC105414, MGC139754, Resistance to inhibitors of cholinesterase 4 homolog, RIC 4, RIC4, SEC9, SNAP 25, SNAP-25B, SNP 25, sp, Synaptosomal associated 25 kDa protein, Synaptosomal associated protein, Synaptosomal Associated Protein 25, Synaptosomal associated protein 25kDa., SNP0601-10 µg, SNP0601-20 µg, SNP0601-50 µg, SNP0601-100 µg, SNP0601-250 µg, SNP0601-500 µg, SNP0601-1 mg, SNP0601-10, SNP0601-20, SNP0601-50, SNP0601-100, SNP0601-250, SNP0601-500, SNP0601-1
References & Citations
Tafoya LC., et al. (2006) J. Neurosci . 26 (30) :7826-38.; ; Schulz JR., . (1998) J. Biol Chem. 273 (38) :24355-9.
Other References
Kull S et al., Isolation and functional characterization of the novel Clostridium botulinum neurotoxin A8 subtype. (PLoS One. 2015) {https://pubmed.ncbi.nlm.nih.gov/25658638/}; ; von Berg L et al., Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology. (Sci Rep. 2019) {https://pubmed.ncbi.nlm.nih.gov/30940836/}; ; Steinberg M et al., Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array. (ALTEX. 2025) {https://pubmed.ncbi.nlm.nih.gov/40396553/}
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 50 mM HEPES buffer (pH 7.4) containing 5mM DTT, 100 mM NaCl
Scientific Category
Neuroscience
NCBI Accession Number
NP_570824.1
Uniprot Accession Number
P60880
Species
Human
AA Sequence
MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG

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