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Recombinant human PSMA7 protein

CAT: 0112-PSM0901-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-PSM0901-020Size:20 µg
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Description
Proteasome alpha 7, PSMA7, is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. PSMA7, belonged to the peptidase T1A family, is a 20S core alpha subunit of proteasome. This protein was found to interact specifically with two subdomains of HIF-1alpha and inhibited the transactivation function of HIF-1alpha under both normoxic and hypoxia-mimicking conditions. Recombinant PSMA7 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Proteasome alpha 7 subunit, C6, HSPC, MGC3755, RC6-1, XAPC7, Proteasome alpha 7 subunit, PSMA7, Proteasome alpha 7 subunit Proteasome (prosome macropain) subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, PSMA 7, RC6 1, Proteasome subunit RC6 1, Proteasome subunit XAPC7.
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
30 kDa (268aa) confirmed by MALDI-TOF
Additionnal Information
PSMA7, Proteasome alpha 7 subunit, C6, HSPC, MGC3755, RC6-1, XAPC7, Proteasome alpha 7 subunit, PSMA7, Proteasome alpha 7 subunit Proteasome (prosome macropain) subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, PSMA 7, RC6 1, Proteasome subunit RC6 1, Proteasome subunit XAPC7., PSM0901-10 µg, PSM0901-20 µg, PSM0901-50 µg, PSM0901-100 µg, PSM0901-250 µg, PSM0901-500 µg, PSM0901-1 mg, PSM0901-10, PSM0901-20, PSM0901-50, PSM0901-100, PSM0901-250, PSM0901-500, PSM0901-1
References & Citations
Cho S., et al. (2001) FEBS Lett. 498 (1) :62-6.; ; Dong J, et al. (2004) J Biol Chem. 279 (20) :21334-42.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_002783
Uniprot Accession Number
O14818
Species
Human
AA Sequence
MSYDRAITVF SPDGHLFQVE YAQEAVKKGS TAVGVRGRDI VVLGVEKKSV AKLQDERTVR KICALDDNVC MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE FLEKNYTDEA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQSLKIL NPEEIEKYVA EIEKEKEENE KKKQKKAS

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