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Recombinant human CKS2 protein

CAT: 0112-CKS0801-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-CKS0801-020Size:20 µg
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Description
CKS2, also known as CDC28 Protein kinase 2 associates with the catalytic subunit of cyclin-dependent kinases and has therefore been assumed to play a direct role in cell cycle regulation. The function of CKS2 in somatic mammalian cells is not well understood although it is required for the first metaphase/anaphase transition during the meiosis. Emerging evidence shows that elevated expression of CKS2 protects the cells from apoptosis. Recombinant CKS2 fused with T7-tag was expressed in E. coli and purified by conventional chromatography techniques.
Product Name Alternative
Cyclin-dependent kinases regulatory subunit 2, CKSHS2, CKS2, CKS1 (S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2, CDC28 protein kinase regulatory subunit 2, CDC28 Protein kinase 2
Expression System
E.coli
Antigen Species
Human
Tag
T7-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
11.3 kDa (94aa) confirmed by MALDI-TOF
Additionnal Information
Cyclin-dependent kinases regulatory subunit 2, Cyclin dependent kinases regulatory subunit 2, CKSHS2, CKS2, CKS1 (S. cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2, CKS 2, CDC28 protein kinase regulatory subunit 2, CDC28 Protein kinase 2, , CKS0801-10 µg, CKS0801-20 µg, CKS0801-50 µg, CKS0801-100 µg, CKS0801-250 µg, CKS0801-500 µg, CKS0801-1 mg, CKS0801-010, CKS0801-020, CKS0801-050, CKS0801-100, CKS0801-250, CKS0801-500, CKS0801-01M
References & Citations
Martinsson-Ahlzen HS., et al: (2008) Mol Cell Biol. 28 (18) :5698-709.; ; Lan Y., et al: (2008) Int J Cancer. 123 (3) :543-51.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 20% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_001818
Uniprot Accession Number
P33552
Species
Human
AA Sequence
MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRR LGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQK

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