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Recombinant human CD9 protein

CAT: 0112-ATGP4064-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP4064-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD9, also known as TSPAN-29, is a member of tetraspanin family. It is found on the surface of exosomes. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. It seems CD9 has a varying role in different types of cancers. The over expression of CD9 was shown to decrease metastasis in certain types of melanoma, breast, lung, pancreas and colon carcinomas. However in other studies, CD9 has been shown to increase migration or be highly expressed in metastatic cancers in various cell lines such as lung cancer, scirrhous-type gastric cancer, hepatocellular carcinoma, acute lymphoblastic leukemia and breast cancer. Recombinant human CD9, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques
Product Name Alternative
CD9 antigen, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29, BA2,5H9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, p24, CD9 antigen isoform1
Expression System
HEK293
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS - PAGE
Molecular Weight
10.7kDa (93aa)
Additionnal Information
ATGP4064-10 µg, ATGP4064-20 µg, ATGP4064-50 µg, ATGP4064-100 µg, ATGP4064-250 µg, ATGP4064-500 µg, ATGP4064-1 mg, ATGP4064-10, ATGP4064-20, ATGP4064-50, ATGP4064-100, ATGP4064-250, ATGP4064-500, ATGP4064-1
References & Citations
Sara J, Eileen M, et al. (2001) . Thromb Haemost. 85 (1) :134-141.; ; Rubinstein E, Billard M, et al. (1993) . Thrombosis Research. 71 (5) : 377–383.; ; Blake DJ, Martiszus JD, et al. (2018) . Cytokine. 111: 567–570.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
Scientific Category
Cardiovascular
NCBI Accession Number
NP_001760.1
Uniprot Accession Number
P21926
Species
Human
N Terminal Sequence
Asp
AA Sequence
SHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI

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