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Recombinant human CD5 protein

CAT: 0112-ATGP3534-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3534-050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD5, as known as T-cell surface glycoprotein CD5, is a transmembrane glycoprotein in the scavenger receptor superfamily. This protein was found expressed in small lymphocytic lymphoma, hairy cell leukemia and mantle cell lymphoma cells. CD5 expression on developing thymocytes is positively regulated by signaling through the T cell antigen receptor and is up-regulated peripheral CD4+ cell. Also, its Signaling inhibits the generation of regulatory T cells but promotes the development of Th17 cells. Recombinant human CD5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
T-cell surface glycoprotein CD5, CD5, LEU1, T1
Expression System
Baculovirus
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
40kDa (359aa)
Additionnal Information
CD5, T-cell surface glycoprotein CD5, CD5, LEU1, T1, ATGP3534-10 µg, ATGP3534-20 µg, ATGP3534-50 µg, ATGP3534-100 µg, ATGP3534-250 µg, ATGP3534-500 µg, ATGP3534-1 mg, ATGP3534-10, ATGP3534-20, ATGP3534-50, ATGP3534-100, ATGP3534-250, ATGP3534-500, ATGP3534-1
References & Citations
Cenit MC., et al, (2014) PLoS ONE 9:E113090.; ; Alinari L., et al, (2016) Am. J. Hematol. 91:395-399.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_055022
Uniprot Accession Number
P06127
Species
Human
N Terminal Sequence
Ala
AA Sequence
ADPEFRLSWY DPDFQARLTR SNSKCQGQLE VYLKDGWHMV CSQSWGRSSK QWEDPSQASK VCQRLNCGVP LSLGPFLVTY TPQSSIICYG QLGSFSNCSH SRNDMCHSLG LTCLEPQKTT PPTTRPPPTT TPEPTAPPRL QLVAQSGGQH CAGVVEFYSG SLGGTISYEA QDKTQDLENF LCNNLQCGSF LKHLPETEAG RAQDPGEPRE HQPLPIQWKI QNSSCTSLEH CFRKIKPQKS GRVLALLCSG FQPKVQSRLV GGSSICEGTV EVRQGAQWAA LCDSSSARSS LRWEEVCREQ QCGSVNSYRV LDAGDPTSRG LFCPHQKLSQ CHELWERNSY CKKVFVTCQD PNPHHHHHH

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