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Recombinant mouse Podocalyxin protein

CAT: 0112-ATGP3311-010Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3311-010Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PODXL, also known as Podocalyxin, is a heavily glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. This protein involved in the regulation of both adhesion and cell morphology and cancer progression. It has to function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Also, it acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Recombinant mouse PODXL, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
Podocalyxin, AW121214, Ly102, PC, PCLP-1, Pclp1
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
41kDa (391aa)
Additionnal Information
Podocalyxin, Podocalyxin, AW121214, Ly102, PC, PCLP-1, Pclp1, ATGP3311-10 µg, ATGP3311-20 µg, ATGP3311-50 µg, ATGP3311-100 µg, ATGP3311-250 µg, ATGP3311-500 µg, ATGP3311-1 mg, ATGP3311-10, ATGP3311-20, ATGP3311-50, ATGP3311-100, ATGP3311-250, ATGP3311-500, ATGP3311-1
References & Citations
Vitureira N., et al. (2010) PLoS ONE 8:e12003.; ; Nielsen JS., et al. (2007) PLoS ONE 2:E237.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_038751
Uniprot Accession Number
Q9R0M4
Species
Mouse
N Terminal Sequence
His22
AA Sequence
HNGNETSTSA IKSSTVQSHQ SATTSTEVTT GHPVASTLAS TQPSNPTPFT TSTQSPSMPT STPNPTSNQS GGNLTSSVSE VDKTKTSSPS STAFTSSSGQ TASSGGKSGD SFTTAPTTTL GLINVSSQPT DLNTTSKLLS TPTTDNTTSP QQPVDSSPST ASHPVGQHTP AAVPSSSGST PSTDNSTLTW KPTTHKPLGT SEATQPLTSQ TPGITTLPVS TLQQSMASTV GTTTEEFTHL ISNGTPVAPP GPSTPSPIWA FGNYQLNCEP PIRPDEELLI LNLTRASLCE RSPLDEKEKL VELLCHSVKA SFKPAEDLCT LHVAPILDNQ AVAVKRIIIE TKLSPKAVYE LLKDRWDDLT EAGVSDMKLG KEGPPEVNED RFSLEHHHHH H

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