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Recombinant mouse TIE2/TEK protein

CAT: 0112-ATGP3190-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3190-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TEK, also known as angiopoietin-1 receptor isoform 2, is cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4. It regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton. This protein effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Recombinant mouse TEK, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Name Alternative
TEK, TEK receptor tyrosine kinase, VMCM, venous malformations, multiple cutaneous and mucosal, TEK tyrosine kinase, endothelial, TIE2, TIE-2, VMCM1, CD202b, angiopoietin-1 receptor, Hyk, AA517024, STK1, p140 TEK
Expression System
Baculovirus
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Molecular Weight
81.6 kDa (730aa)
Additionnal Information
Angiopoietin1 receptor, Tek, Hyk, Tie-2, Tie2, CD202b, AA517024, STK1, ATGP3190-10 µg, ATGP3190-20 µg, ATGP3190-50 µg, ATGP3190-100 µg, ATGP3190-250 µg, ATGP3190-500 µg, ATGP3190-1 mg, ATGP3190-10, ATGP3190-20, ATGP3190-50, ATGP3190-100, ATGP3190-250, ATGP3190-500, ATGP3190-1
References & Citations
Horita K et al., (1992) Biochem. Biophys. Res. Commun. 189 (3) :1747-1753.; ; Dumont DJ et al., (1992) Oncogene 7 (8) :1471-1480.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_001277478
Uniprot Accession Number
Q02858
Species
Mouse

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