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Recombinant mouse LRPAP protein

CAT: 0112-ATGP3133-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3133-100Size:100 µg
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Description
Lrpap1 also known as Alpha-2-macroglobulin receptor-associated protein. The alpha-2-macroglobulin receptor-associated protein (RAP) is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. Lrpap1 acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. Lrpap1 may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. Recombinant mouse Lspap1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Alpha-2-macroglobulin receptor-associated protein, Alpha 2 macroglobulin receptor associated protein, AA617339, AI790446, AU042172, C77774, HBP44, RAP
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 90% by SDS-PAGE
Molecular Weight
41.4 kDa (355aa) confirmed by MALDI-TOF
Additionnal Information
LRPAP, Alpha-2-macroglobulin receptor-associated protein, Alpha 2 macroglobulin receptor associated protein, AA617339, AI790446, AU042172, C77774, HBP44, RAP, ATGP3133-10 µg, ATGP3133-20 µg, ATGP3133-50 µg, ATGP3133-100 µg, ATGP3133-250 µg, ATGP3133-500 µg, ATGP3133-1 mg, ATGP3133-10, ATGP3133-20, ATGP3133-50, ATGP3133-100, ATGP3133-250, ATGP3133-500, ATGP3133-1
References & Citations
Strickland D.K., et al. (1991) J. Biol. Chem. 266:13364-13369. ; ; Van Leuven F., et al. (1998) Genomics 52:145-151.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_038615
Uniprot Accession Number
P55302
Species
Mouse
AA Sequence
QPIAGHG GKYSREKNEP EMAAKRESGE EFRMEKLNQL WEKAKRLHLS PVRLAELHSD LKIQERDELN WKKLKVEGLD KDGEKEAKLI HNLNVILARY GLDGRKDAQM VHSNALNEDT QDELGDPRLE KLWHKAKTSG KFSSEELDKL WREFLHYKEK IQEYNVLLDT LSRAEEGYEN LLSPSDMAHI KSDTLISKHS ELKDRLRSIN QGLDRLRKVS HQGYGSTTEF EEPRVIDLWD LAQSANFTEK ELESFREELK HFEAKIEKHN HYQKQLEISH QKLKHVESIG DPEHISRNKE KYVLLEEKTK ELGYKVKKHL QDLSSRVSRA RHNEL

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