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Recombinant human IFIT3 protein

CAT: 0112-ATGP3114-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3114-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IFIT3 also known as Interferon-induced protein with tetratricopeptiede repeats 3 isoform a. IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. IFIT3 is significantly induced upon RNA virus infection. Ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IRF3-mediated gene expression. Recombinant human IFIT3 was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
Interferon-induced protein with tetratricopeptiede repeats 3 isoform a, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by absorbance at 280 nm)
Purity
> 85% by SDS-PAGE
Molecular Weight
58.4 kDa (513aa)
Additionnal Information
IFIT3, Interferon-induced protein with tetratricopeptiede repeats 3 isoform a, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, ATGP3114-10 µg, ATGP3114-20 µg, ATGP3114-50 µg, ATGP3114-100 µg, ATGP3114-250 µg, ATGP3114-500 µg, ATGP3114-1 mg, ATGP3114-10, ATGP3114-20, ATGP3114-50, ATGP3114-100, ATGP3114-250, ATGP3114-500, ATGP3114-1
References & Citations
Fensterl V., et al. (2011) J. Interferon Cytokine Res. 31:71-78.; ; Liu X.Y., et al. (2011) J. Immunol. 187:2559-2568.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001540
Uniprot Accession Number
O14879
Species
Human
AA Sequence
MSEVTKN SLEKILPQLK CHFTWNLFKE DSVSRDLEDR VCNQIEFLNT EFKATMYNLL AYIKHLDGNN EAALECLRQA EELIQQEHAD QAEIRSLVTW GNYAWVYYHL GRLSDAQIYV DKVKQTCKKF SNPYSIEYSE LDCEEGWTQL KCGRNERAKV CFEKALEEKP NNPEFSSGLA IAMYHLDNHP EKQFSTDVLK QAIELSPDNQ YVKVLLGLKL QKMNKEAEGE QFVEEALEKS PCQTDVLRSA AKFYRRKGDL DKAIELFQRV LESTPNNGYL YHQIGCCYKA KVRQMQNTGE SEASGNKEMI EALKQYAMDY SNKALEKGLN PLNAYSDLAE FLETECYQTP FNKEVPDAEK QQSHQRYCNL QKYNGKSEDT AVQHGLEGLS ISKKSTDKEE IKDQPQNVSE NLLPQNAPNY WYLQGLIHKQ NGDLLQAAKC YEKELGRLLR DAPSGIGSIF LSASELEDGS EEMGQGAVSS SPRELLSNSE QLN