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Recombinant human CDK5RAP3 protein

CAT: 0112-ATGP3070-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3070-500Size:500 µg
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Description
CDK5RAP3 also known as CDK5 regulatory subunit-associated protein 3. This protein is potential regulator of CDK5 activity via its interaction with CDK5R. Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, nad an activating subunit, p25NCK5A. CDK5RAP3 binds to p25NCK5A and therefore may be involved in neuronal differentiation. Recombinant human CDK5RAP3, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
CDK5 regulatory subunit-associated protein 3 isoform b, C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
59kDa (526aa)
Additionnal Information
CDK5RAP3, CDK5 regulatory subunit-associated protein 3 isoform b, C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553, ATGP3070-10 µg, ATGP3070-20 µg, ATGP3070-50 µg, ATGP3070-100 µg, ATGP3070-250 µg, ATGP3070-500 µg, ATGP3070-1 mg, ATGP3070-10, ATGP3070-20, ATGP3070-50, ATGP3070-100, ATGP3070-250, ATGP3070-500, ATGP3070-1
References & Citations
Kim S., et al. (2014) PLoS One. Jan 22; ;9 (1) :e87016.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT
Scientific Category
Cell Cycle
NCBI Accession Number
NP_788276
Uniprot Accession Number
Q96JB5
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MEDHQHVPID IQTSKLLDWL VDRRHCSLKW QSLVLTIREK INAAIQDMPE SEEIAQLLSG SYIHYFHCLR ILDLLKGTEA STKNIFGRYS SQRMKDWQEI IALYEKDNTY LVELSSLLVR NVNYEIPSLK KQIAKCQQLQ QEYSRKEEEC QAGAAEMREQ FYHSCKQYGI TGENVRGELL ALVKDLPSQL AEIGAAAQQS LGEAIDVYQA SVGFVCESPT EQVLPMLRFV QKRGNSTVYE WRTGTEPSVV ERPHLEELPE QVAEDAIDWG DFGVEAVSEG TDSGISAEAA GIDWGIFPES DSKDPGGDGI DWGDDAVALQ ITVLEAGTQA PEGVARGPDA LTLLEYTETR NQFLDELMEL EIFLAQRAVE LSEEADVLSV SQFQLAPAIL QGQTKEKMVT MVSVLEDLIG KLTSLQLQHL FMILASPRYV DRVTEFLQQK LKQSQLLALK KELMVQKQQE ALEEQAALEP KLDLLLEKTK ELQKLIEADI SKRYSGRPVN LMGTSL

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