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Recombinant human MAGEA8 protein

CAT: 0112-ATGP3052-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP3052-100Size:100 µg
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Description
MAGEA8 also known as Melanoma-associated antigen 8 is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA8, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
Melanoma-associated antigen 8, CT1.8, MAGE8
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
37.6 kDa (341aa) confirmed by MALDI-TOF
Additionnal Information
MAGEA8, Melanoma-associated antigen 8, CT1.8, MAGE8, ATGP3052-10 µg, ATGP3052-20 µg, ATGP3052-50 µg, ATGP3052-100 µg, ATGP3052-250 µg, ATGP3052-500 µg, ATGP3052-1 mg, ATGP3052-10, ATGP3052-20, ATGP3052-50, ATGP3052-100, ATGP3052-250, ATGP3052-500, ATGP3052-1
References & Citations
Serrano A., et al. (1999) Int. J. Cancer 83 (5), 664-669; ; Rogner uC., et al. (1995) Genomics 29 (3), 725-731;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_001159873
Uniprot Accession Number
P43361
Species
Human
AA Sequence
MLLGQKS QRYKAEEGLQ AQGEAPGLMD VQIPTAEEQK AASSSSTLIM GTLEEVTDSG SPSPPQSPEG ASSSLTVTDS TLWSQSDEGS SSNEEEGPST SPDPAHLESL FREALDEKVA ELVRFLLRKY QIKEPVTKAE MLESVIKNYK NHFPDIFSKA SECMQVIFGI DVKEVDPAGH SYILVTCLGL SYDGLLGDDQ STPKTGLLII VLGMILMEGS RAPEEAIWEA LSVMGLYDGR EHSVYWKLRK LLTQEWVQEN YLEYRQAPGS DPVRYEFLWG PRALAETSYV KVLEHVVRVN ARVRISYPSL HEEALGEEKG V