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Recombinant human TRIB3 protein

CAT: 0112-ATGP2922-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2922-250Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRIB3, also known as tribbles pseudokinase 3, is a putative protein kinase that is induced by the transcription factor NF-kappaB. This protein is a negative regulator of NF-kappaB, and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, it can negatively regulate the cell survival serine-threonine kinase AKT1. Recombinant human TRIB3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
Tribbles homolog 3, Tribbles homolog 3, C20orf97, NIPK, SINK, SKIP3, TRB3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
42.0 kDa (381aa)
Additionnal Information
TRIB3, Tribbles homolog 3, Tribbles homolog 3, C20orf97, NIPK, SINK, SKIP3, TRB3, ATGP2922-10 µg, ATGP2922-20 µg, ATGP2922-50 µg, ATGP2922-100 µg, ATGP2922-250 µg, ATGP2922-500 µg, ATGP2922-1 mg, ATGP2922-10, ATGP2922-20, ATGP2922-50, ATGP2922-100, ATGP2922-250, ATGP2922-500, ATGP2922-1
References & Citations
Du K. et al. (2003) Science. 300:1574-1577.; ; Hegedus Z. et al. (2006) Cell Mol Life Sci. 63:1632-1641.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_066981
Uniprot Accession Number
Q96RU7
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMRATPLA APAGSLSRKK RLELDDNLDT ERPVQKRARS GPQPRLPPCL LPLSPPTAPD RATAVATASR LGPYVLLEPE EGGRAYQALH CPTGTEYTCK VYPVQEALAV LEPYARLPPH KHVARPTEVL AGTQLLYAFF TRTHGDMHSL VRSRHRIPEP EAAVLFRQMA TALAHCHQHG LVLRDLKLCR FVFADRERKK LVLENLEDSC VLTGPDDSLW DKHACPAYVG PEILSSRASY SGKAADVWSL GVALFTMLAG HYPFQDSEPV LLFGKIRRGA YALPAGLSAP ARCLVRCLLR REPAERLTAT GILLHPWLRQ DPMPLAPTRS HLWEAAQVVP DGLGLDEARE EEGDREVVLY G

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