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Recombinant human CGREF1 protein

CAT: 0112-ATGP2921-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2921-250Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGREF1, also known as cell growth regulator with EF-hand domain 1, is a secreted calcium ion binding protein. This protein contains two EF-hand domains and both EF-hands are required for function. It is probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides. It mediates cell-cell adhesion in a calcium-dependent manner. In addition, CGREF1 is able to inhibit growth in several cell lines. Recombinant human CGREF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Product Name Alternative
Cell growth regulator with EF-hand domain 1, Cell growth regulator with EF-hand domain 1, CGR11
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
32.3 kDa (305aa) confirmed by MALDI-TOF
Additionnal Information
CGREF1, Cell growth regulator with EF-hand domain 1, Cell growth regulator with EF-hand domain 1, CGR11, ATGP2921-10 µg, ATGP2921-20 µg, ATGP2921-50 µg, ATGP2921-100 µg, ATGP2921-250 µg, ATGP2921-500 µg, ATGP2921-1 mg, ATGP2921-10, ATGP2921-20, ATGP2921-50, ATGP2921-100, ATGP2921-250, ATGP2921-500, ATGP2921-1
References & Citations
Dolcino M. et al. (2012) Clin Dev Immunol. 2012:198956.; ; Madden SL. D.H. et al. (1996) Cancer Res. 56:5384-5390.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4)
Scientific Category
Cell Cycle
NCBI Accession Number
AAH34764
Uniprot Accession Number
Q99674
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSAPKDGVT RPDSEVQHQL LPNPFQPGQE QLGLLQSYLK GLGRTEVQLE HLSREQVLLY LFALHDYDQS GQLDGLELLS MLTAALAPGA ANSPTTNPVI LIVDKVLETQ DLNGDGLMTP AELINFPGVA LRHVEPGEPL APSPQEPQAV GRQSLLAKSP LRQETQEAPG PREEAKGQVE ARRESLDPVQ EPGGQAEADG DVPGPRGEAE GQAEAKGDAP GPRGEAGGQA EAEGDAPGPR GEAGGQAEAR ENGEEAKELP GETLESKNTQ NDFEVHIVQV ENDEI

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