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Recombinant human GLTPD1 protein

CAT: 0112-ATGP2830-004Size: 4 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2830-004Size:4 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GLTPD1 mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. This protein is required for normal structure of the Golgi stacks. GLTPD1 can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0) . It plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Recombinant human GLTPD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Glycolipid transfer protein domain-containing protein 1, CPTP, MGC10334, glycolipid transfer protein domain containing 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.8 kDa (237aa) confirmed by MALDI-TOF
Additionnal Information
GLTPD1, Glycolipid transfer protein domain-containing protein 1, CPTP, MGC10334, glycolipid transfer protein domain containing 1, ATGP2830-10 µg, ATGP2830-20 µg, ATGP2830-50 µg, ATGP2830-100 µg, ATGP2830-250 µg, ATGP2830-500 µg, ATGP2830-1 mg, ATGP2830-10, ATGP2830-20, ATGP2830-50, ATGP2830-100, ATGP2830-250, ATGP2830-500, ATGP2830-1
References & Citations
Simanshu D.K., et al. (2013) Nature 500:463-467.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol, 1mM DTT
Scientific Category
Transportation
NCBI Accession Number
NP_001025056
Uniprot Accession Number
Q5TA50
Species
Human
AA Sequence
MDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLG TIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHW LQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRA VTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAE HSLLDLP

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