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Recombinant human EDAR protein

CAT: 0112-ATGP2829-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2829-020Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EDAR is a member of the tumor necrosis factor receptor family. This protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Recombinant human EDAR protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Name Alternative
Tumor necrosis factor receptor superfamily member EDAR, DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
48.2 kDa (445aa)
Additionnal Information
EDAR, Tumor necrosis factor receptor superfamily member EDAR, DL, ECTD10A, ECTD10B, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1, ATGP2829-10 µg, ATGP2829-20 µg, ATGP2829-50 µg, ATGP2829-100 µg, ATGP2829-250 µg, ATGP2829-500 µg, ATGP2829-1 mg, ATGP2829-10, ATGP2829-20, ATGP2829-50, ATGP2829-100, ATGP2829-250, ATGP2829-500, ATGP2829-1
References & Citations
Yan M., et al. (2000) Science 290:523-527
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_071731
Uniprot Accession Number
Q9UNE0
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSEYSNCGE NEYYNQTTGL CQECPPCGPG EEPYLSCGYG TKDEDYGCVP CPAEKFSKGG YQICRRHKDC EGFFRATVLT PGDMENDAEC GPCLPGYYML ENRPRNIYGM VCYSCLLAPP NTKECVGATS GASANFPGTS GSSTLSPFQH AHKELSGQGH LATALIIAMS TIFIMAIAIV LIIMFYILKT KPSAPACCTS HPGKSVEAQV SKDEEKKEAP DNVVMFSEKD EFEKLTATPA KPTKSENDAS SENEQLLSRS VDSDEEPAPD KQGSPELCLL SLVHLAREKS ATSNKSAGIQ SRRKKILDVY ANVCGVVEGL SPTELPFDCL EKTSRMLSST YNSEKAVVKT WRHLAESFGL KRDEIGGMTD GMQLFDRIST AGYSIPELLT KLVQIERLDA VESLCADILE WAGVVPPASQ PHAAS

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