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Recombinant human PPA2 protein

CAT: 0112-ATGP2771-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2771-500Size:500 µg
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Description
PPA2 is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Recombinant human PPA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Inorganic pyrophosphatase 2 mitochondrial isoform 1, Inorganic pyrophosphatase 2, mitochondrial isoform 1, Pyrophosphatase (inorganic) 2, HSPC124, SID6-306
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
37.1 kDa (325aa) confirmed by MALDI-TOF
Additionnal Information
PPA2, Inorganic pyrophosphatase 2 mitochondrial isoform 1, Inorganic pyrophosphatase 2, mitochondrial isoform 1, Pyrophosphatase (inorganic) 2, HSPC124, SID6-306, ATGP2771-10 µg, ATGP2771-20 µg, ATGP2771-50 µg, ATGP2771-100 µg, ATGP2771-250 µg, ATGP2771-500 µg, ATGP2771-1 mg, ATGP2771-10, ATGP2771-20, ATGP2771-50, ATGP2771-100, ATGP2771-250, ATGP2771-500, ATGP2771-1
References & Citations
Gauthier-Campbell C., Bredt D.S., et al. (2004) Mol. Biol. Cell 15:2205-2217
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Metabolism
NCBI Accession Number
NP_789845
Uniprot Accession Number
Q9H2U2
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSALYHTEE RGQPCSQNYR LFFKNVTGHY ISPFHDIPLK VNSKEENGIP MKKARNDEYE NLFNMIVEIP RWTNAKMEIA TKEPMNPIKQ YVKDGKLRYV ANIFPYKGYI WNYGTLPQTW EDPHEKDKST NCFGDNDPID VCEIGSKILS CGEVIHVKIL GILALIDEGE TDWKLIAINA NDPEASKFHD IDDVKKFKPG YLEATLNWFR LYKVPDGKPE NQFAFNGEFK NKAFALEVIK STHQCWKALL MKKCNGGAIN CTNVQISDSP FRCTQEEARS LVESVSSSPN KESNEEEQVW HFLGK

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