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Recombinant human FBXO2 protein

CAT: 0112-ATGP2752-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2752-050Size:50 µg
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Description
FBXO2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. This protein belongs to the Fbxs class. It is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. Recombinant human FBXO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
F-box only protein 2, FBG1, Fbs1, FBX2, NFB42, OCP1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
35.7 kDa (319aa) confirmed by MALDI-TOF
Additionnal Information
FBXO2, F-box only protein 2, FBG1, Fbs1, FBX2, NFB42, OCP1, ATGP2752-10 µg, ATGP2752-20 µg, ATGP2752-50 µg, ATGP2752-100 µg, ATGP2752-250 µg, ATGP2752-500 µg, ATGP2752-1 mg, ATGP2752-10, ATGP2752-20, ATGP2752-50, ATGP2752-100, ATGP2752-250, ATGP2752-500, ATGP2752-1
References & Citations
Cenciarelli C., et al (1999) . Curr. Biol. 9:1177-1179; ; Burkard T.R., et al (2011) . BMC Syst. Biol. 5:17-17;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Scientific Category
Ubiquitination
NCBI Accession Number
NP_036300
Uniprot Accession Number
Q9UK22
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMDGDGDP ESVGQPEEAS PEEQPEEASA EEERPEDQQE EEAAAAAAYL DELPEPLLLR VLAALPAAEL VQACRLVCLR WKELVDGAPL WLLKCQQEGL VPEGGVEEER DHWQQFYFLS KRRRNLLRNP CGEEDLEGWC DVEHGGDGWR VEELPGDSGV EFTHDESVKK YFASSFEWCR KAQVIDLQAE GYWEELLDTT QPAIVVKDWY SGRSDAGCLY ELTVKLLSEH ENVLAEFSSG QVAVPQDSDG GGWMEISHTF TDYGPGVRFV RFEHGGQDSV YWKGWFGARV TNSSVWVEP

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