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Recombinant human Vitronectin protein

CAT: 0112-ATGP2741-050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2741-050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vitronectin, also known as VTN, is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. Increased expression of VTN, integrins and plasminogen activators has been observed in migrating cells during wound healing. Recombinant human VTN protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
VTN, VN, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B, Somatomedin B, Complement S-protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
54.7 kDa (482aa)
Additionnal Information
VTN, Vitronectin precursor, V75, VN, VNT, ATGP2741-10 µg, ATGP2741-20 µg, ATGP2741-50 µg, ATGP2741-100 µg, ATGP2741-250 µg, ATGP2741-500 µg, ATGP2741-1 mg, ATGP2741-10, ATGP2741-20, ATGP2741-50, ATGP2741-100, ATGP2741-250, ATGP2741-500, ATGP2741-1
References & Citations
Chain D., et al. (1991) FEBS Lett. 285: 251-256.; ; Cherny R C., et al. (1993) J Biol Chem. 268: 9725-9729.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cardiovascular
NCBI Accession Number
NP_000629
Uniprot Accession Number
P04004
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSDQESCKG RCTEGFNVDK KCQCDELCSY YQSCCTDYTA ECKPQVTRGD VFTMPEDEYT VYDDGEEKNN ATVHEQVGGP SLTSDLQAQS KGNPEQTPVL KPEEEAPAPE VGASKPEGID SRPETLHPGR PQPPAEEELC SGKPFDAFTD LKNGSLFAFR GQYCYELDEK AVRPGYPKLI RDVWGIEGPI DAAFTRINCQ GKTYLFKGSQ YWRFEDGVLD PDYPRNISDG FDGIPDNVDA ALALPAHSYS GRERVYFFKG KQYWEYQFQH QPSQEECEGS SLSAVFEHFA MMQRDSWEDI FELLFWGRTS AGTRQPQFIS RDWHGVPGQV DAAMAGRIYI SGMAPRPSLA KKQRFRHRNR KGYRSQRGHS RGRNQNSRRP SRATWLSLFS SEESNLGANN YDDYRMDWLV PATCEPIQSV FFFSGDKYYR VNLRTRRVDT VDPPYPRSIA QYWLGCPAPG HL

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