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Recombinant human STRADA protein

CAT: 0112-ATGP2722-500Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP2722-500Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STE20-related kinase adapter protein alpha isoform 5, also known as STRADA, is a member of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRADA-LKB1 interaction results in phosphorylation of STRADA and enhanced autophosphorylation of LKB1. Recombinant human STRADA protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Name Alternative
STE20-related kinase adapter protein alpha isoform 5, LYK5, NY-BR-96, PMSE, Stlk, STRAD
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
37 kDa (337aa)
Additionnal Information
STRADA, STE20-related kinase adapter protein alpha isoform 5, LYK5, NY-BR-96, PMSE, Stlk, STRAD, ATGP2722-10 µg, ATGP2722-20 µg, ATGP2722-50 µg, ATGP2722-100 µg, ATGP2722-250 µg, ATGP2722-500 µg, ATGP2722-1 mg, ATGP2722-10, ATGP2722-20, ATGP2722-50, ATGP2722-100, ATGP2722-250, ATGP2722-500, ATGP2722-1
References & Citations
Avizienyte E., et al. (1998) Cancer Res. 58: 2087-2090.; ; Baas A F., et al. (2003) EMBO J. 22: 3062-3072.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_001159441
Uniprot Accession Number
Q7RTN6
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSFLVSK PERIRTNDAS SESIASFSKQ EVMSSFLPEG GCYELLTVIG KGFEDLMTVN LARYKPTGEY VTVRRINLEA CSNEMVTFLQ GELHVSKLFN HPNIVPYRAT FIADNELWVV TSFMAYGSAK DLICTHFMDG MNELAIAYIL QGVLKALDYI HHMGYVHRSV KASHILISVD GKVYLSGLRS NLSMISHGQR QRVVHDFPKY SVKVLPWLSP EVLQQNLQGY DAKSDIYSVG ITACELANGH VPFKDMPATQ MLLEKLNGTV PCLLDTSTIP AEELTMSPSR SVANSGLSDS LTTSTPRPSN GPVPAPS

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