STRADA cDNA

CAT: 0112-ATGD0156-010Size: 10 µgDry Ice: NoHazardous: No
CAT#:0112-ATGD0156-010Size:10 µg
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Description
STRADA encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. STRADA forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25) . STRADA activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. STRADA is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.
Product Name Alternative
LYK5, NY-BR-96, PMSE, Stlk, STRAD
Chromosomal Location
17q23.3
Antigen Species
Human
Vector Type
PATGen (puc19-derived cloning vector)
Sequence
ATGTCATTTCTTGTAAGTAAACCAGAGCGAATCAGGACCAATGATGCGAGCTCAGAGTCAATAGCATCCTTCTCTAAACAGGAGGTCATGAGTAGCTTTCTGCCAGAGGGAGGGTGTTACGAGCTGCTCACTGTGATAGGCAAAGGATTTGAGGACCTGATGACTGTGAATCTAGCAAGGTACAAACCAACAGGAGAGTACGTGACTGTACGGAGGATTAACCTAGAAGCTTGTTCCAATGAGATGGTAACATTCTTGCAGGGCGAGCTGCATGTCTCCAAACTCTTCAACCATCCCAATATCGTGCCATATCGAGCCACTTTTATTGCAGACAATGAGCTGTGGGTTGTCACATCATTCATGGCATACGGTTCTGCAAAAGATCTCATCTGTACACACTTCATGGATGGCATGAATGAGCTGGCGATTGCTTACATCCTGCAGGGGGTGCTGAAGGCCCTCGACTACATCCACCACATGGGATATGTACACAGGAGTGTCAAAGCCAGCCACATCCTGATCTCTGTGGATGGGAAGGTCTACCTGTCTGGTTTGCGCAGCAACCTCAGCATGATAAGCCATGGGCAGCGGCAGCGAGTGGTCCACGATTTTCCCAAGTACAGTGTCAAGGTTCTGCCGTGGCTCAGCCCCGAGGTCCTCCAGCAGAATCTCCAGGGTTATGATGCCAAGTCTGACATCTACAGTGTGGGAATCACAGCCTGTGAACTGGCCAACGGCCATGTCCCCTTTAAGGATATGCCTGCCACCCAGATGCTGCTAGAGAAACTGAACGGCACAGTGCCCTGCCTGTTGGATACCAGCACCATCCCCGCTGAGGAGCTGACCATGAGCCCTTCGCGCTCAGTGGCCAACTCTGGCCTGAGTGACAGCCTGACCACCAGCACCCCCCGGCCCTCCAACGGCCCAGTGCCAGCACCCTCCTGA
Additionnal Information
STRADA, LYK5, NY-BR-96, PMSE, Stlk, STRAD, STRADA, ATGD0156-10 µg, ATGD0156-20 µg, ATGD0156-50 µg, ATGD0156-100 µg, ATGD0156-250 µg, ATGD0156-500 µg, ATGD0156-1 mg, ATGD0156-10, ATGD0156-20, ATGD0156-50, ATGD0156-100, ATGD0156-250, ATGD0156-500, ATGD0156-1
Storage Conditions
Store the plasmid at -20C.
Formulation
Lyophilized
Scientific Category
Cell Cycle
Omim
608626
NCBI Accession Number
NP_001159441.1
Species
Human
Preparation
1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.
RNA Reference
NM_001165969.1
DNA Size
945bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

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