Products for Research Use Only
RegisterLogin

Recombinant human DNMT3L protein

CAT: 0112-ATGP2696-010Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0112-ATGP2696-010Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. DNMT3L is a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. It also mediates transcriptional repression through interaction with histone deacetylase 1. Recombinant human DNMT3L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Name Alternative
DNA (cytosine-5) -methyltransferase 3-like isoform 2, DNA (cytosine-5-) -methyltransferase 3-like
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
46.2 kDa (411aa) confirmed by MALDI-TOF
Additionnal Information
DNMT3L, DNA (cytosine-5) -methyltransferase 3-like isoform 2, DNA (cytosine-5-) -methyltransferase 3-like, ATGP2696-10 µg, ATGP2696-20 µg, ATGP2696-50 µg, ATGP2696-100 µg, ATGP2696-250 µg, ATGP2696-500 µg, ATGP2696-1 mg, ATGP2696-10, ATGP2696-20, ATGP2696-50, ATGP2696-100, ATGP2696-250, ATGP2696-500, ATGP2696-1
References & Citations
Ooi S.K., Qiu C, et al. (2007) Nature 448:714-717;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_787063
Uniprot Accession Number
Q9UJW3
Species
Human
AA Sequence
MAAIP ALDPEAEPSM DVILVGSSEL SSSVSPGTGR DLIAYEVKAN QRNIEDICIC CGSLQVHTQH PLFEGGICAP CKDKFLDALF LYDDDGYQSY CSICCSGETL LICGNPDCTR CYCFECVDSL VGPGTSGKVH AMSNWVCYLC LPSSRSGLLQ RRRKWRSQLK AFYDRESENP LEMFETVPVW RRQPVRVLSL FEDIKKELTS LGFLESGSDP GQLKHVVDVT DTVRKDVEEW GPFDLVYGAT PPLGHTCDRP PSWYLFQFHR LLQYARPKPG SPRPFFWMFV DNLVLNKEDL DVASRFLEME PVTIPDVHGG SLQNAVRVWS NIPAIRSRHW ALVSEEELSL LAQNKQSSKL AAKWPTKLVK NCFLPLREYF KYFSTELTSS L

Related Products

CatalogName
TPM0701-500Recombinant human TPMT protein
TPM0701-100Recombinant human TPMT protein
TPD0501-020Recombinant human TPD52L1 protein
SNP0902-500Recombinant human Syntaphilin protein
SNP0901-050Recombinant human SNAP23 protein
SNP0801-020Recombinant human SNAP25 protein
SNP0601-100Recombinant human SNAP25 protein
SNA0901-020Recombinant human SNAPIN protein
SMD0901-500Recombinant human Smad4 protein
RCV0501-020Recombinant human Recoverin protein

Alternative Products

CatalogName
PROTQ9UJW3-01Human DNMT3L Recombinant Protein
ARP1909-01Recombinant Human DNMT3L Protein
RP009667DNMT3L Recombinant Protein (Human)
MBS388132-01Recombinant DNMT3L protein
32-2279-10DNMT3L Recombinant Protein
P6948-01Recombinant Human Dnmt3L
E45H35042M5DNMT3L (NM_175867) Human Recombinant Protein
PH32557I5DNMT3L (NM_013369) Human Recombinant Protein

Popular Products